Research for Rare - Research for rare diseases

Dystonias (DysTract)

The dystonias comprise a heterogeneous group of incurable movement disorders with variable age of onset, body distribution, and genetic background sharing the core clinical features of twisting, repetitive movements or abnormal postures. There is a pressing clinical need for better therapies in dystonias, which cause lifelong disability, often in children and young adults.

The consortium will combine human clinical and experimental animal research including cutting edge technologies such as iPS cell (induced pluripotent stem cells) characterization from human patients to describe the entire disease path of dystonia from a molecular level to brain network abnormalities. This coherent view is expected to boost our understanding of these model circuitry disorders of the brain and to open up new avenues for better treatment of persons with dystonia. Patients will immediately benefit from this consortium through standardizing the diagnosis and treatment approach to dystonia and establishing a reference database for all groups involved in dystonia care.

Prof. Dr. med. Jens Volkmann (coordinating investigator)
Department of Neurology
University Hospital of Würzburg
Josef-Schneider-Str.11; D-97080 WÜRZBURG
Tel. +49 (931)20123751; Fax.+49 (931)20123946

Prof. Dr. med. Christine Klein
University of Lübeck; Institute of Neurogenetics
Ratzeburger Allee 160; 23538 Lübeck
Phone: +49-451-2903351; Fax: +49-451-2903355


Forschung hilft heilen! Das Beispiel der Idiopathischen Torsionsdystonie

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