Research for Rare - Research for rare diseases

Leukonet – Network for Leukodystrophies

Leukodystrophies are rare diseases affecting myelin. They are dominated by neurological symptoms which frequently cause death. Curative treatment is not available. Clinical research projects of Leukonet describe natural history of classified leukodystrophies and try to define new entities among so far unclassified leukodystrophies. Natural history data support ongoing and future clinical trials in collaboration with the biotech-industry and will be applied for concomitant therapy evaluation of bone marrow transplantation in certain disorders. Leukonet intends internationalizing patient registries for selected disorders to broaden data base. Basic science projects characterize newly discovered leukodystrophy causing genes, study pathogenesis in leukodystrophy mouse models, analyse patients genetically and develop new therapeutic strategies.

Projekte
Kontakt
Prof. Dr. med. Volkmar Gieselmann
Institut für Biochemie und Molekularbiologie
Universität Bonn
Nussallee 11
53115 Bonn
Tel: 0228 / 732411
Fax: 0228 / 732416
E-Mail: gieselmann@ibmb.uni-bonn.de
www.leukonet.de
Publications